DNA Binding Motif

Accessions: 1qqa_A (3D-footprint 20231221)
Names: PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Length: 8
Consensus: CGCangCg
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 0 96 0 G
03 4 81 4 7 C
04 38 19 20 19 a
05 24 24 24 24 n
06 21 23 31 21 g
07 2 88 2 4 C
08 12 12 60 12 g
Binding TFs: 1qqa_A (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: 1qqa_M
Publications: Glasfeld A, Koehler A.N, Schumacher M.A, Brennan R.G. The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. Journal of molecular biology 291:347-61 (1999). [Pubmed]

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