DNA Binding Motif

						

			
Accessions: 1o4x_B (3D-footprint 20231221)

			
Names: Transcription factor SOX-2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
Length: 6
Consensus: gCAAAG
Weblogo: 
PSSM: P0      A      C      G      T
01      9     19     48     20      g
02      9     67     11      9      C
03     96      0      0      0      A
04     96      0      0      0      A
05     96      0      0      0      A
06      0      9     87      0      G
Binding TFs: 1o4x_B (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 1o4x_C
1o4x_D
			
Publications: Williams D.C, Cai M, Clore G.M. Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. The Journal of biological chemistry 279:1449-57 (2004). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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