DNA Binding Motif

						

			
Accessions: CUX1_RFX5_1 (HumanTF2 1.0)

			
Names: CUX1_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: rATCrATagsmdtrCwTaGyAAC
Weblogo: 
PSSM: P0      A      C      G      T
01    360    148    510    173      r
02    870      2      8     40      A
03      2      2      1    870      T
04     21    870      2     35      C
05    423     12    447     36      r
06    870      0      4     40      A
07    145      0      0    870      T
08    383    171    165    150      a
09    207    121    365    177      g
10    214    232    270    154      s
11    270    285    115    199      m
12    219    123    285    242      d
13    160    210    137    363      t
14    306    135    344     85      r
15     64    648     83     76      C
16    320    184    115    250      w
17     33    147     24    666      T
18    658     77    212     37      a
19    179     56    870    111      G
20     51    518     18    352      y
21    870     58    107     86      A
22    870     37     63    153      A
23     24    870     19    107      C
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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