DNA Binding Motif

						

			
Accessions: CUX1_HOXA13_1 (HumanTF2 1.0), UN0486.1 (JASPAR 2024)

			
Names: CUX1_HOXA13, CUX1::HOXA13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: ATCGATyAysycrTmAA
Weblogo: 
PSSM: P0      A      C      G      T
01    556      0      6     48      A
02      0      0      0    556      T
03     10    556      0     57      C
04     52     32    505      2      G
05    556      0      0      9      A
06      7      0     19    556      T
07     20    245      6    285      y
08    487     26     15     28      A
09     35    245     44    232      y
10     29    290    221     16      s
11     22    275     39    281      y
12    163    556    108    171      c
13    305     17    251     10      r
14      1     15     16    556      T
15    556    261     35    125      m
16    556     41     16     63      A
17    556      4     20     32      A
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
HOXA13_TF2 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
P39880 (Homeobox domain, CUT domain, Homeobox KN domain)
P39880
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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