DNA Binding Motif

						

			
Accessions: GltC (DBTBS 1.0)

			
Names: GltC
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 15
Consensus: ATCTCAWTTWGAGAT
Weblogo: 
PSSM: P0      A      C      G      T
01      1      0      0      0      A
02      0      0      0      1      T
03      0      1      0      0      C
04      0      0      0      1      T
05   0.21   0.79      0      0      C
06      1      0      0      0      A
07   0.31      0      0   0.69      W
08      0      0      0      1      T
09      0      0      0      1      T
10   0.31      0      0   0.69      W
11      0      0   0.79   0.21      G
12      1      0      0      0      A
13      0      0   0.79   0.21      G
14      1      0      0      0      A
15      0      0      0      1      T
Binding TFs: GltC (Bacterial regulatory helix-turn-helix protein, lysR family, LysR substrate binding domain)
Binding Sites: gltA_1
gltC_1
			
Publications: Belitsky B.R, Janssen P.J, Sonenshein A.L. Sites required for GltC-dependent regulation of Bacillus subtilis glutamate synthase expression. Journal of bacteriology 177:5686-95 (1995). [Pubmed]


Picossi S, Belitsky B.R, Sonenshein A.L. Molecular mechanism of the regulation of Bacillus subtilis gltAB expression by GltC. Journal of molecular biology 365:1298-313 (2007). [Pubmed]


Commichau F.M, Herzberg C, Tripal P, Valerius O, Stülke J. A regulatory protein-protein interaction governs glutamate biosynthesis in Bacillus subtilis: the glutamate dehydrogenase RocG moonlights in controlling the transcription factor GltC. Molecular microbiology 65:642-54 (2007). [Pubmed]


Bohannon D.E, Sonenshein A.L. Positive regulation of glutamate biosynthesis in Bacillus subtilis. Journal of bacteriology 171:4718-27 (1989). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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