DNA Binding Motif

Accessions: 3zkc_AB (3D-footprint 20231221)
Names: HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the master regulator for biofilm formation SinR in complex with DNA.
Length: 15
Consensus: GTTCtnnnnGnGAaC
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 0 96 T
03 0 0 0 96 T
04 0 96 0 0 C
05 10 16 17 53 t
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 1 10 69 16 G
11 24 24 24 24 n
12 0 0 96 0 G
13 86 10 0 0 A
14 64 10 10 12 a
15 16 75 0 5 C
Type: Heterodimer
Binding TFs: 3zkc_A (Helix-turn-helix, Helix-turn-helix domain, Cro/C1-type HTH DNA-binding domain, Helix-turn-helix domain)
3zkc_B (Helix-turn-helix, Helix-turn-helix domain, Cro/C1-type HTH DNA-binding domain, Helix-turn-helix domain)
Binding Sites: 3zkc_C
3zkc_D
Publications: Newman J.A, Rodrigues C, Lewis R.J. Molecular basis of the activity of SinR protein, the master regulator of biofilm formation in Bacillus subtilis. The Journal of biological chemistry 288:10766-78 (2013). [Pubmed]

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