DNA Binding Motif

Accessions: 2o93_LMO (3D-footprint 20210203)
Names: actor of activated T-cells, cytoplasmic 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
Length: 24
Consensus: GGGAnnTTCCGnnnnnnnnnTTCC
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 96 0 G
03 0 0 96 0 G
04 73 7 9 7 A
05 24 24 24 24 n
06 24 24 24 24 n
07 7 7 7 75 T
08 0 0 0 96 T
09 0 96 0 0 C
10 0 96 0 0 C
11 7 7 75 7 G
12 24 24 24 24 n
13 24 24 24 24 n
14 24 24 24 24 n
15 24 24 24 24 n
16 24 24 24 24 n
17 24 24 24 24 n
18 24 24 24 24 n
19 24 24 24 24 n
20 24 24 24 24 n
21 7 7 7 75 T
22 0 0 0 96 T
23 0 96 0 0 C
24 0 96 0 0 C
Type: Heterodimer
Binding TFs: 2o93_M (Rel homology domain (RHD), IPT/TIG domain)
2o93_O / 2o93_L (Rel homology domain (RHD), IPT/TIG domain)
Binding Sites: 2o93_A
2o93_B
Publications: Bates D.L, Barthel K.K, Wu Y, Kalhor R, Stroud J.C, Giffin M.J, Chen L. Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element. Structure (London, England : 1993) 16:684-94 (2008). [Pubmed]

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