DNA Binding Motif

						

			
Accessions: CUX2_DBD_2 (HumanTF 1.0), MA0755.1 (JASPAR 2024)

			
Names: CUX2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 10
Consensus: TrATCRATaa
Weblogo: 
PSSM: P0      A      C      G      T
01   8111   4573   4247  45569      T
02  45569   5067  23534  12191      r
03  45569    250    540    345      A
04    479   1841    485  45569      T
05     74  45569     94    736      C
06  13767    208  31803    395      R
07  45569     69    163    191      A
08    396    278     66  45569      T
09  45569  11730   7587  12097      a
10  19809   9534   5056  11171      a
Type: Heterodimer
Binding TFs: CUX2_DBD (Homeobox domain, CUT domain, Homeobox KN domain)
O14529 (Homeobox domain, CUT domain, Homeobox KN domain)
O14529
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Harada R., Berube G., Tamplin O. J., Denis-Larose C., Nepveu A. DNA-binding specificity of the cut repeats from the human cut-like protein. Mol. Cell. Biol. 15:129-140 (1995). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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