DNA Binding Motif

Accessions: 4mhg_A (3D-footprint 20231221)
Names: Transcription factor ETV6
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ETV6 bound to a specific DNA sequence
Length: 8
Consensus: anCCGGAA
Weblogo:
PSSM: P0 A C G T
01 54 13 16 13 a
02 24 24 24 24 n
03 0 96 0 0 C
04 0 83 0 13 C
05 0 0 96 0 G
06 0 0 96 0 G
07 68 0 13 15 A
08 96 0 0 0 A
Binding TFs: 4mhg_A (Ets-domain)
Binding Sites: 4mhg_B
4mhg_C
Publications: De S, Chan A.C, Coyne H.J, Bhachech N, Hermsdorf U, Okon M, Murphy M.E, Graves B.J, McIntosh L.P. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. Journal of molecular biology 426:1390-406 (2014). [Pubmed]

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