DNA Binding Motif

Accessions: 4x9j_A (3D-footprint 20210203)
Names: Early growth response protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: EGR-1 with Doubly Methylated DNA
Length: 10
Consensus: annCCCAnnC
Weblogo:
PSSM: P0 A C G T
01 38 19 19 20 a
02 24 24 24 24 n
03 24 24 24 24 n
04 0 96 0 0 C
05 0 96 0 0 C
06 0 96 0 0 C
07 96 0 0 0 A
08 24 24 24 24 n
09 24 24 24 24 n
10 0 77 0 19 C
Binding TFs: 4x9j_A (C2H2-type zinc finger, Zinc finger, C2H2 type, Zinc-finger double domain)
Binding Sites: 4x9j_B
4x9j_C
Publications: Zandarashvili L, White MA, Esadze A, Iwahara J. Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1. FEBS Lett 589:1748-53 (2015). [Pubmed]

Disclaimer

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research.