DNA Binding Motif

Accessions: 4r2c_A (3D-footprint 20210203)
Names: Early growth response protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Egr1/Zif268 zinc fingers in complex with hydroxymethylated DNA
Length: 9
Consensus: GCGTGGGGt
Weblogo:
PSSM: P0 A C G T
01 0 0 76 20 G
02 0 96 0 0 C
03 0 0 96 0 G
04 0 0 0 96 T
05 0 0 96 0 G
06 0 0 96 0 G
07 0 0 96 0 G
08 0 0 96 0 G
09 20 19 19 38 t
Binding TFs: 4r2c_A (C2H2-type zinc finger, Zinc finger, C2H2 type, Zinc-finger double domain)
Binding Sites: 4r2c_B
4r2c_C
Publications: Hashimoto H, Olanrewaju Y.O, Zheng Y, Wilson G.G, Zhang X, Cheng X. Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes & development 28:2304-13 (2014). [Pubmed]

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