DNA Binding Motif

Accessions: 6p0u_ABEF (3D-footprint 20210203)
Names: DNA-binding protein Fis
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ternary DNA complex " FX(1-2)-2Xis" containing E. coli Fis and phage lambda Xis
Length: 21
Consensus: AnnnnTGTGTTnnnnACMGCC
Weblogo:
PSSM: P0 A C G T
01 86 3 3 4 A
02 24 24 24 24 n
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 0 0 0 96 T
07 0 0 96 0 G
08 3 3 1 89 T
09 10 7 76 3 G
10 0 13 9 74 T
11 9 3 11 73 T
12 24 24 24 24 n
13 24 24 24 24 n
14 24 24 24 24 n
15 24 24 24 24 n
16 90 1 4 1 A
17 0 96 0 0 C
18 26 67 0 3 M
19 10 5 72 9 G
20 11 84 0 1 C
21 0 96 0 0 C
Type: Heterodimer
Binding TFs: 6p0u_A (Bacterial regulatory protein, Fis family)
6p0u_B (Bacterial regulatory protein, Fis family)
Binding Sites: 6p0u_C
6p0u_D
Publications: Hancock SP, Cascio D, Johnson RC. Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res 47:8874-8887 (2019). [Pubmed]

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