DNA Binding Motif

						

			
Accessions: 4r2s_A (3D-footprint 20231221)

			
Names: Wilms tumor protein, isoform 4/CRA_a
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Wilms Tumor Protein (WT1) Q369P zinc fingers in complex with methylated DNA
Length: 10
Consensus: annCCCACGC
Weblogo: 
PSSM: P0      A      C      G      T
01     56     13     13     14      a
02     24     24     24     24      n
03     24     24     24     24      n
04      4     88      2      2      C
05      0     96      0      0      C
06      0     96      0      0      C
07     96      0      0      0      A
08      7     74      7      8      C
09      0      0     96      0      G
10      9     69      9      9      C
Binding TFs: 4r2s_A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4r2s_B
4r2s_C
			
Publications: Hashimoto H, Olanrewaju Y.O, Zheng Y, Wilson G.G, Zhang X, Cheng X. Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes & development 28:2304-13 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.