DNA Binding Motif

Accessions: Hpr (DBTBS 1.0)
Names: Hpr
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 9
Consensus: rATATymyT
Weblogo:
PSSM: P0 A C G T
01 0.59 0 0.41 0 r
02 0.79 0.10 0.10 0 A
03 0 0.11 0 0.89 T
04 1 0 0 0 A
05 0.05 0 0.11 0.84 T
06 0.03 0.34 0 0.62 y
07 0.67 0.33 0 0 m
08 0.04 0.33 0 0.63 y
09 0 0 0.23 0.77 T
Binding TFs: Hpr (PTS HPr component phosphorylation site)
Binding Sites: aprE_3
aprE_4
aprE_5
aprE_6
epr_1
nprE_1
nprE_2
sinI_2
sinI_3
yclF_1
yclF_2
Publications: Ferrari E, Howard S.M, Hoch J.A. Effect of stage 0 sporulation mutations on subtilisin expression. Journal of bacteriology 166:173-9 (1986). [Pubmed]

Higerd T.B, Hoch J.A, Spizizen J. Hyperprotease-producing mutants of Bacillus subtilis. Journal of bacteriology 112:1026-8 (1972). [Pubmed]

Henner D.J, Ferrari E, Perego M, Hoch J.A. Location of the targets of the hpr-97, sacU32(Hy), and sacQ36(Hy) mutations in upstream regions of the subtilisin promoter. Journal of bacteriology 170:296-300 (1988). [Pubmed]

Kallio P.T, Fagelson J.E, Hoch J.A, Strauch M.A. The transition state regulator Hpr of Bacillus subtilis is a DNA-binding protein. The Journal of biological chemistry 266:13411-7 (1991). [Pubmed]

Kodgire P, Dixit M, Rao K.K. ScoC and SinR negatively regulate epr by corepression in Bacillus subtilis. Journal of bacteriology 188:6425-8 (2006). [Pubmed]

Shafikhani S.H, Mandic-Mulec I, Strauch M.A, Smith I, Leighton T. Postexponential regulation of sin operon expression in Bacillus subtilis. Journal of bacteriology 184:564-71 (2002). [Pubmed]

Caldwell R, Sapolsky R, Weyler W, Maile R.R, Causey S.C, Ferrari E. Correlation between Bacillus subtilis scoC phenotype and gene expression determined using microarrays for transcriptome analysis. Journal of bacteriology 183:7329-40 (2001). [Pubmed]

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