DNA Binding Motif

						

			
Accessions: 4umm_AE (3D-footprint 20231221)

			
Names: ECR-USP
Organisms: Heliothis virescens, Tobacco budworm moth
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: The Cryo-EM structure of the palindromic DNA-bound USP-EcR nuclear receptor reveals an asymmetric organization with allosteric domain positioning
Length: 11
Consensus: GTtCAntnnAC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0      0     96      T
03     12     12      8     64      t
04      0     96      0      0      C
05     83      6      7      0      A
06     24     24     24     24      n
07     12     12      8     64      t
08     24     24     24     24      n
09     24     24     24     24      n
10     70     14      6      6      A
11      0     96      0      0      C
Type: Heterodimer
Binding TFs: 4umm_A (Zinc finger, C4 type (two domains))
4umm_E (Zinc finger, C4 type (two domains))
Binding Sites: 4umm_C
4umm_D
			
Publications: Maletta M, Orlov I, Roblin P, Beck Y, Moras D, Billas I.M, Klaholz B.P. The palindromic DNA-bound USP/EcR nuclear receptor adopts an asymmetric organization with allosteric domain positioning. Nature communications 5:4139 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.