DNA Binding Motif

Accessions: 5yel_A (3D-footprint 2022-04-03)
Names: Transcriptional repressor CTCF
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of CTCF ZFs6-11-gb7CSE
Length: 22
Consensus: ACTGgnnnnnnnnGGTACnGCA
Weblogo:
PSSM: P0 A C G T
01 86 3 3 4 A
02 0 90 3 3 C
03 3 4 15 74 T
04 0 0 96 0 G
05 3 16 65 12 g
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 24 24 24 24 n
14 1 0 80 15 G
15 0 0 96 0 G
16 0 0 4 92 T
17 87 3 3 3 A
18 16 74 3 3 C
19 24 24 24 24 n
20 0 0 96 0 G
21 0 96 0 0 C
22 92 3 0 1 A
Binding TFs: 5yel_A (Zinc finger, C2H2 type, LIM domain, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 5yel_E
5yel_F
Publications: Yin M, Wang J, Wang M, Li X, Zhang M, Wu Q, Wang Y. Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites. Cell Res 27:1365-1377 (2017). [Pubmed]

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