DNA Binding Motif

						

			
Accessions: ZIC1_full (HumanTF 1.0), MA0696.1 (JASPAR 2024)

			
Names: ZIC1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 14
Consensus: gACCCCCyGCTGyG
Weblogo: 
PSSM: P0      A      C      G      T
01   1113   3934  25702   8960      g
02  22722   2660   7408     23      A
03    836  28949     58    125      C
04   1264  29217    204    281      C
05   2606  25527    327    927      C
06      0  29399      4      7      C
07    185  29532     10     14      C
08     22  18412      0  10313      y
09   2156     45  31995     14      G
10     23  27426    439   6735      C
11   1215   1757   5531  27084      T
12     73     24  34649      1      G
13   3121   7693   1690  16190      y
14     35    520  34431   2725      G
Type: Heterodimer
Binding TFs: ZIC1_full (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q15915 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q15915
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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