DNA Binding Motif

Accessions: 5k5h_A (3D-footprint 2022-04-03)
Names: Transcriptional repressor CTCF
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure
Length: 12
Consensus: CGCCCCCTGCcG
Weblogo:
PSSM: P0 A C G T
01 12 74 5 5 C
02 5 1 85 5 G
03 0 96 0 0 C
04 0 96 0 0 C
05 5 90 1 0 C
06 0 96 0 0 C
07 0 96 0 0 C
08 0 0 0 96 T
09 0 0 96 0 G
10 10 74 7 5 C
11 5 64 6 21 c
12 5 12 69 10 G
Binding TFs: 5k5h_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc-finger domain)
Binding Sites: 5k5h_B
5k5h_C
Publications: Hashimoto H, Wang D, Horton JR, Zhang X, Corces VG, Cheng X. Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol Cell 66:711-720 (2017). [Pubmed]

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