DNA Binding Motif

						

			
Accessions: HSF2_DBD (HumanTF 1.0), MA0770.1 (JASPAR 2024)

			
Names: HSF2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: trimeric; SELEX cycle: 3, HT-SELEX
Length: 13
Consensus: TTCTAGAAyrTTC
Weblogo: 
PSSM: P0      A      C      G      T
01    173     37     91   3187      T
02     23      2     47   3187      T
03     16   3187      2      0      C
04      1    710    293   3187      T
05   3187    565    792      0      A
06      2      0   3187      1      G
07   3187     49      4     28      A
08   3187      1     23    108      A
09    170   1406    630    981      y
10    999    468   1209    511      r
11    142     68     88   3187      T
12     45     89     43   3187      T
13     89   3187    117    364      C
Type: Heterodimer
Binding TFs: Q03933 (HSF-type DNA-binding, Vertebrate heat shock transcription factor)
HSF2_DBD (HSF-type DNA-binding)
Q03933
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Manuel M., Rallu M., Loones M. T., Zimarino V., Mezger V., Morange M. Determination of the consensus binding sequence for the purified embryonic heat shock factor 2.. Eur. J. Biochem. 269:2527-2537 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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