DNA Binding Motif

Accessions: 1lat_AB (3D-footprint 20231221)
Names: GLUCOCORTICOID RECEPTOR
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: GLUCOCORTICOID RECEPTOR MUTANT/DNA COMPLEX
Length: 11
Consensus: gGrACATGwTC
Weblogo:
PSSM: P0 A C G T
01 16 8 64 8 g
02 0 0 96 0 G
03 56 8 24 8 r
04 96 0 0 0 A
05 0 96 0 0 C
06 96 0 0 0 A
07 0 0 0 96 T
08 0 0 96 0 G
09 24 16 8 48 w
10 0 0 0 96 T
11 0 96 0 0 C
Type: Heterodimer
Binding TFs: 1lat_A (Zinc finger, C4 type (two domains))
1lat_B (Zinc finger, C4 type (two domains))
Binding Sites: 1lat_C / 1lat_D
Publications: Gewirth D.T, Sigler P.B. The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex. Nature structural biology 2:386-94 (1995). [Pubmed]

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