DNA Binding Motif

Accessions: 4is1_CD (3D-footprint 20231221)
Names: Zinc finger protein 217
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ZNF217 bound to DNA
Length: 18
Consensus: TGCAGAATnnATTCTGCA
Weblogo:
PSSM: P0 A C G T
01 3 6 3 84 T
02 3 3 87 3 G
03 0 96 0 0 C
04 96 0 0 0 A
05 0 0 96 0 G
06 96 0 0 0 A
07 84 3 6 3 A
08 3 3 6 84 T
09 24 24 24 24 n
10 24 24 24 24 n
11 84 3 6 3 A
12 3 3 6 84 T
13 0 0 0 96 T
14 0 96 0 0 C
15 0 0 0 96 T
16 0 0 96 0 G
17 10 80 3 3 C
18 87 3 3 3 A
Type: Heterodimer
Binding TFs: 4is1_C (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
4is1_D (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4is1_A / 4is1_B
Publications: Vandevenne M, Jacques D.A, Artuz C, Nguyen C.D, Kwan A.H, Segal D.J, Matthews J.M, Crossley M, Guss J.M, Mackay J.P. New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. The Journal of biological chemistry 288:10616-27 (2013). [Pubmed]

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