DNA Binding Motif

Accessions: 4wk8_FG (3D-footprint 20231221)
Names: Forkhead box protein P3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: FOXP3 forms a domain-swapped dimer to bridge DNA
Length: 5
Consensus: ATTTG
Weblogo:
PSSM: P0 A C G T
01 67 11 9 9 A
02 9 9 9 69 T
03 0 0 0 96 T
04 0 0 0 96 T
05 11 9 67 9 G
Binding TFs: 4wk8_F / 4wk8_G (Fork head domain)
Binding Sites: 4wk8_B
4wk8_A
Publications: Chen Y, Chen C, Zhang Z, Liu C.C, Johnson M.E, Espinoza C.A, Edsall L.E, Ren B, Zhou X.J, Grant S.F, Wells A.D, Chen L. DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions. Nucleic acids research 43:1268-82 (2015). [Pubmed]

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