DNA Binding Motif

Accessions: MA0149.1 (JASPAR 2018)
Names: EWSR1-FLI1
Organisms: Homo sapiens
Libraries: JASPAR 2018 1
1 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Cheneby , Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2017) JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Res. doi: 10.1093/nar/gkx1126 [Pubmed]
Notes: ChIP-seq
Length: 18
Consensus: GGAAGGAAGGAAGGAAGG
Weblogo:
PSSM: P0 A C G T
01 0 0 105 0 G
02 2 0 103 0 G
03 104 0 1 0 A
04 104 0 1 0 A
05 1 0 104 0 G
06 2 0 102 1 G
07 103 0 2 0 A
08 102 0 3 0 A
09 0 0 104 1 G
10 0 2 103 0 G
11 99 4 2 0 A
12 105 0 0 0 A
13 0 0 105 0 G
14 0 2 103 0 G
15 100 3 0 2 A
16 102 0 2 1 A
17 5 0 97 3 G
18 3 3 97 2 G
Binding TFs: F1JVV8 (Ets-domain)
Binding Sites: MA0149.1.14 / MA0149.1.18 / MA0149.1.11 / MA0149.1.7 / MA0149.1.1 / MA0149.1.2 / MA0149.1.5 / MA0149.1.10
MA0149.1.9 / MA0149.1.20 / MA0149.1.6 / MA0149.1.12
MA0149.1.13
MA0149.1.15
MA0149.1.16
MA0149.1.17
MA0149.1.19
MA0149.1.3
MA0149.1.4
MA0149.1.8
Publications: Guillon N, Tirode F, Boeva V, Zynovyev A, Barillot E, Delattre O. The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation function. PloS one 4:e4932 (2009). [Pubmed]

Disclaimer

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research.