DNA Binding Motif

Accessions: UP00373A_2 (UniPROBE 20160601), UP00382A_2 (UniPROBE 20160601)
Names: MXL-1_MDL-1
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: twdasCACGTGskawb
Weblogo:
PSSM: P0 A C G T
01 0.16 0.23 0.15 0.46 t
02 0.30 0.19 0.23 0.28 w
03 0.28 0.12 0.27 0.33 d
04 0.46 0.13 0.24 0.18 a
05 0.08 0.43 0.42 0.07 s
06 0.01 0.99 0 0 C
07 0.98 0 0 0.01 A
08 0 0.96 0 0.03 C
09 0.02 0 0.98 0 G
10 0 0.01 0 0.98 T
11 0 0 0.99 0.01 G
12 0.10 0.43 0.41 0.06 s
13 0.12 0.20 0.32 0.36 k
14 0.45 0.18 0.19 0.18 a
15 0.33 0.20 0.17 0.30 w
16 0.20 0.29 0.26 0.25 b
Type: Heterodimer
Binding TFs: UP00373A (Helix-loop-helix DNA-binding domain)
UP00382A (Helix-loop-helix DNA-binding domain)
Binding Sites: AACACGTG
ACACGTGC
ACACGTGG
ACCACGTG
AGCACGTG
ATCACGTG
CACGTGAC
CACGTGCA
CACGTGCC
CACGTGCG
CACGTGGA
CACGTGGC
CACGTGGG
CACGTGTC
CCACGTGA
CCACGTGC
CCACGTGG
GCACGTGA
GCACGTGC
TCACGTGA
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

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