DNA Binding Motif

Accessions: 1au7_A (3D-footprint 20231221)
Names: PROTEIN PIT-1
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: PIT-1 MUTANT/DNA COMPLEX
Length: 11
Consensus: TGTATATaCAT
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 96 0 G
03 6 6 12 72 T
04 96 0 0 0 A
05 0 0 0 96 T
06 96 0 0 0 A
07 12 6 8 70 T
08 57 14 6 19 a
09 0 96 0 0 C
10 76 0 12 8 A
11 0 0 0 96 T
Binding TFs: 1au7_A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: 1au7_C
1au7_D
Publications: Jacobson E.M, Li P, Leon-del-Rio A, Rosenfeld M.G, Aggarwal A.K. Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. Genes & development 11:198-212 (1997). [Pubmed]

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