DNA Binding Motif

Accessions: CLOCK_BHLHA15 (HumanTF2 1.0)
Names: CLOCK_BHLHA15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: wCAYGTGkcyarCAyrTGs
Weblogo:
PSSM: P0 A C G T
01 486 335 349 452 w
02 201 1622 0 8 C
03 1622 0 15 22 A
04 0 1622 17 554 Y
05 303 5 1622 0 G
06 43 151 9 1622 T
07 3 4 1622 310 G
08 180 332 665 444 k
09 380 818 266 157 c
10 209 497 233 683 y
11 890 216 266 249 a
12 606 405 540 71 r
13 81 1622 85 0 C
14 1622 196 74 44 A
15 33 874 207 1622 y
16 1622 200 870 17 r
17 240 177 23 1622 T
18 23 23 1622 248 G
19 13 608 666 335 s
Type: Heterodimer
Binding TFs: BHLHA15_TF2 (Helix-loop-helix DNA-binding domain)
CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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