DNA Binding Motif

						

			
Accessions: 1jj4_AB (3D-footprint 20231221)

			
Names: Regulatory protein E2
Organisms: Human papillomavirus type 18
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human papillomavirus type 18 E2 DNA-binding domain bound to its DNA target
Length: 16
Consensus: CAACCGnntnCGGTTG
Weblogo: 
PSSM: P0      A      C      G      T
01      2     90      2      2      C
02     70      3     14      9      A
03     96      0      0      0      A
04      2     93      0      1      C
05      0     96      0      0      C
06     16      2     74      4      G
07     24     24     24     24      n
08     24     24     24     24      n
09     11     11     16     58      t
10     24     24     24     24      n
11      2     88      2      4      C
12      0      0     96      0      G
13      0      0     96      0      G
14      0      0      0     96      T
15      2     16      2     76      T
16      2      2     90      2      G
Type: Heterodimer
Binding TFs: 1jj4_A (E2 (early) protein, C terminal)
1jj4_B (E2 (early) protein, C terminal)
Binding Sites: 1jj4_C / 1jj4_D
			
Publications: Kim S.S, Tam J.K, Wang A.F, Hegde R.S. The structural basis of DNA target discrimination by papillomavirus E2 proteins. The Journal of biological chemistry 275:31245-54 (2000). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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