DNA Binding Motif

Accessions: MA1123.1 (JASPAR 2024)
Names: TWIST1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 13
Consensus: awwCCAGATGTby
Weblogo:
PSSM: P0 A C G T
01 5396 3892 4497 4354 a
02 5158 3843 3831 5307 w
03 5112 2815 3693 6519 w
04 2642 13244 1703 550 C
05 210 17703 100 126 C
06 17749 81 145 164 A
07 237 914 16142 846 G
08 16400 1053 544 142 A
09 177 273 166 17523 T
10 228 241 17332 338 G
11 1029 1798 2516 12796 T
12 2589 4683 5181 5686 b
13 4322 4726 4194 4897 y
Type: Heterodimer
Binding TFs: Q15672 (Helix-loop-helix DNA-binding domain)
Q15672
Binding Sites: MA1123.1.1
MA1123.1.10
MA1123.1.11
MA1123.1.12
MA1123.1.13
MA1123.1.14
MA1123.1.15
MA1123.1.16
MA1123.1.17
MA1123.1.18
MA1123.1.19
MA1123.1.2
MA1123.1.20
MA1123.1.3
MA1123.1.4
MA1123.1.5
MA1123.1.6
MA1123.1.7
MA1123.1.8
MA1123.1.9
Publications: Chang AT, Liu Y, Ayyanathan K, Benner C, Jiang Y, Prokop JW, Paz H, Wang D, Li HR, Fu XD, Rauscher FJ 3rd, Yang J. An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors. Genes Dev 29:603-16 (2015). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.