DNA Binding Motif

Accessions: 4ihv_AB (3D-footprint 20231221)
Names: DNA-binding protein fis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Fis bound to 27 bp sequence DNA F28 (AAATTTGTTTGAGCGTTGAGCAAATTT)
Length: 17
Consensus: TGtnTGnnnnnTrnnCA
Weblogo:
PSSM: P0 A C G T
01 3 5 3 85 T
02 0 0 96 0 G
03 10 10 15 61 t
04 24 24 24 24 n
05 3 13 3 77 T
06 5 3 85 3 G
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 5 3 3 85 T
13 60 3 30 3 r
14 24 24 24 24 n
15 24 24 24 24 n
16 0 96 0 0 C
17 85 5 3 3 A
Type: Heterodimer
Binding TFs: 4ihv_A (Bacterial regulatory protein, Fis family)
4ihv_B (Bacterial regulatory protein, Fis family)
Binding Sites: 4ihv_C
4ihv_D
Publications: Hancock S.P, Ghane T, Cascio D, Rohs R, Di Felice R, Johnson R.C. Control of DNA minor groove width and Fis protein binding by the purine 2-amino group. Nucleic acids research 41:6750-60 (2013). [Pubmed]

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