DNA Binding Motif

						

			
Accessions: HSF4_DBD (HumanTF 1.0), MA0771.1 (JASPAR 2024)

			
Names: HSF4
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: trimeric; SELEX cycle: 3, HT-SELEX
Length: 13
Consensus: TTCtrGAAyrTTC
Weblogo: 
PSSM: P0      A      C      G      T
01   1918   1026   1116  10067      T
02    728     91    985  10067      T
03     94  10067    111     70      C
04     62   4329   3252  10067      t
05  10067   4012   4790     33      r
06      3     12  10067      8      G
07  10067    832     49    837      A
08  10067    414    369   1654      A
09   1356   3686   2184   2841      y
10   2602   2220   3325   1920      r
11   1317    284    384  10067      T
12    320     80    136  10067      T
13     98  10067    100    213      C
Type: Heterodimer
Binding TFs: HSF4_DBD (HSF-type DNA-binding)
Q9ULV5 (HSF-type DNA-binding)
Q9ULV5
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Funikov SIu, Garbuz DG, Zatsepina OG. [Kinetics of heat shock response upon disfunction of general transcription factor (HSF)]. Mol Biol (Mosk) 48:306-13 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.