DNA Binding Motif

						

			
Accessions: ZNF282_DBD (HumanTF 1.0), MA1154.1 (JASPAR 2024)

			
Names: ZNF282
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4; Possibly partial, HT-SELEX
Length: 17
Consensus: cTTTCCCmyAACACkas
Weblogo: 
PSSM: P0      A      C      G      T
01     21    196     50     45      c
02     39     21      7    378      T
03     16      0      8    387      T
04      3      2      3    380      T
05      0    209      2      0      C
06      0    208      0      1      C
07      0    205      3      2      C
08    140     99      0     21      m
09     12    132      2    126      y
10    256      3     37     61      A
11    277      0      0      2      A
12      2    210      4      3      C
13    242     44      2      7      A
14      1    210      2      2      C
15     14      0    297    129      k
16    157     40     60     43      a
17     44     98     97     51      s
Type: Heterodimer
Binding TFs: ZNF282_DBD (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q9UDV7 (Zinc finger, C2H2 type, KRAB box, Zinc finger protein , Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q9UDV7
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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