DNA Binding Motif

Accessions: 5v0l_A (3D-footprint 20231221)
Names: Aryl hydrocarbon receptor nuclear translocator
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the AHR-ARNT heterodimer in complex with the DRE
Length: 5
Consensus: wsAnC
Weblogo:
PSSM: P0 A C G T
01 30 12 6 48 w
02 6 48 24 18 s
03 78 18 0 0 A
04 24 24 24 24 n
05 0 90 0 6 C
Binding TFs: 5v0l_A (Helix-loop-helix DNA-binding domain, PAS fold)
Binding Sites: 5v0l_C
5v0l_D
Publications: Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc Natl Acad Sci U S A 114:5431-5436 (2017). [Pubmed]

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