DNA Binding Motif

						

			
Accessions: CodY (DBTBS 1.0)

			
Names: CodY
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 11
Consensus: AAAAAksckGA
Weblogo: 
PSSM: P0      A      C      G      T
01      1      0      0      0      A
02      1      0      0      0      A
03      1      0      0      0      A
04      1      0      0      0      A
05      1      0      0      0      A
06   0.19      0   0.37   0.43      k
07      0   0.50   0.50      0      s
08   0.17   0.66      0   0.17      c
09      0      0   0.37   0.63      k
10      0      0      1      0      G
11   0.77      0      0   0.23      A
Binding TFs: CodY (CodY GAF-like domain, CodY helix-turn-helix domain, HTH domain)
Binding Sites: comK_2
dppA_2
hag_1
hutP_4
ilvB_2
srfAA_1
			
Publications: Serror P, Sonenshein A.L. CodY is required for nutritional repression of Bacillus subtilis genetic competence. Journal of bacteriology 178:5910-5 (1996). [Pubmed]


Serror P, Sonenshein A.L. Interaction of CodY, a novel Bacillus subtilis DNA-binding protein, with the dpp promoter region. Molecular microbiology 20:843-52 (1996). [Pubmed]


Bergara F, Ibarra C, Iwamasa J, Patarroyo J.C, Aguilera R, Márquez-Magaña L.M. CodY is a nutritional repressor of flagellar gene expression in Bacillus subtilis. Journal of bacteriology 185:3118-26 (2003). [Pubmed]


Fisher S.H, Rohrer K, Ferson A.E. Role of CodY in regulation of the Bacillus subtilis hut operon. Journal of bacteriology 178:3779-84 (1996). [Pubmed]


Molle V, Nakaura Y, Shivers R.P, Yamaguchi H, Losick R, Fujita Y, Sonenshein A.L. Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis. Journal of bacteriology 185:1911-22 (2003). [Pubmed]


Mäder U, Hennig S, Hecker M, Homuth G. Transcriptional organization and posttranscriptional regulation of the Bacillus subtilis branched-chain amino acid biosynthesis genes. Journal of bacteriology 186:2240-52 (2004). [Pubmed]


Shivers R.P, Sonenshein A.L. Activation of the Bacillus subtilis global regulator CodY by direct interaction with branched-chain amino acids. Molecular microbiology 53:599-611 (2004). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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