DNA Binding Motif

						

			
Accessions: TFAP2A_DBD_2 (HumanTF 1.0), MA0003.3 (JASPAR 2024)

			
Names: TFAP2A
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 11
Consensus: hGCCysAGGCw
Weblogo: 
PSSM: P0      A      C      G      T
01   1706   1939    277   1386      h
02    137    968   4340     47      G
03      0   5309    139      0      C
04      0   5309     11    281      C
05     33   1646    658   2972      y
06    575   2682   1613    438      s
07   3640    995    618     56      A
08   1012    224   5309      0      G
09      0     31   5309      0      G
10     31   4726    582     21      C
11   1865    798   1295   1350      w
Type: Heterodimer
Binding TFs: P05549 (Transcription factor AP-2)
TFAP2A_DBD (Transcription factor AP-2)
P05549
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Eckert D, Buhl S, Weber S, Jäger R, Schorle H. The AP-2 family of transcription factors. Genome Biol : (2005;6(13):246.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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