DNA Binding Motif

Accessions: 4nqa_HI (3D-footprint 20231221)
Names: Retinoic acid receptor RXR-alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA
Length: 15
Consensus: GnCCCnnnGTnnCCC
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 24 24 24 24 n
03 0 96 0 0 C
04 12 72 6 6 C
05 0 84 6 6 C
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 6 6 78 6 G
10 6 6 6 78 T
11 24 24 24 24 n
12 24 24 24 24 n
13 0 96 0 0 C
14 0 96 0 0 C
15 6 72 6 12 C
Type: Heterodimer
Binding TFs: 4nqa_H (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
4nqa_I (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Binding Sites: 4nqa_L
4nqa_M
Publications: Lou X, Toresson G, Benod C, Suh J.H, Philips K.J, Webb P, Gustafsson J.A. Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA. Nature structural & molecular biology 21:277-81 (2014). [Pubmed]

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