DNA Binding Motif

Accessions: 4mte_ABCD (3D-footprint 20231221)
Names: Zinc uptake regulation protein
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Zinc Uptake Regulator Complexed with Zinc and DNA
Length: 20
Consensus: TGAnATGnTATAATATCACA
Weblogo:
PSSM: P0 A C G T
01 3 3 3 87 T
02 0 0 96 0 G
03 81 6 3 6 A
04 24 24 24 24 n
05 82 3 5 6 A
06 0 0 0 96 T
07 0 0 96 0 G
08 24 24 24 24 n
09 0 0 0 96 T
10 96 0 0 0 A
11 0 0 0 96 T
12 96 0 0 0 A
13 74 6 10 6 A
14 0 17 0 79 T
15 96 0 0 0 A
16 6 6 6 78 T
17 6 68 12 10 C
18 96 0 0 0 A
19 0 96 0 0 C
20 96 0 0 0 A
Type: Heterodimer
Binding TFs: 4mte_A (Ferric uptake regulator family)
4mte_B (Ferric uptake regulator family)
4mte_C (Ferric uptake regulator family)
4mte_D (Ferric uptake regulator family)
Binding Sites: 4mte_Y
4mte_Z
Publications: Gilston B.A, Wang S, Marcus M.D, Canalizo-Hernández M.A, Swindell E.P, Xue Y, Mondragón A, O'Halloran T.V. Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon. PLoS biology 12:e1001987 (2014). [Pubmed]

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