DNA Binding Motif

Accessions: 1r4i_AB (3D-footprint 20210203)
Names: Androgen receptor
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of Androgen Receptor DNA-Binding Domain Bound to a Direct Repeat Response Element
Length: 11
Consensus: ACAnnnaGTnC
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 0 96 0 0 C
03 96 0 0 0 A
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 60 12 12 12 a
08 0 0 96 0 G
09 12 0 12 72 T
10 24 24 24 24 n
11 12 72 0 12 C
Type: Heterodimer
Binding TFs: 1r4i_A (Zinc finger, C4 type (two domains))
1r4i_B (Zinc finger, C4 type (two domains))
Binding Sites: 1r4i_C
1r4i_D
Publications: Shaffer P.L, Jivan A, Dollins D.E, Claessens F, Gewirth D.T. Structural basis of androgen receptor binding to selective androgen response elements. Proceedings of the National Academy of Sciences of the United States of America 101:4758-63 (2004). [Pubmed]

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