DNA Binding Motif

Accessions: 3p57_AB (3D-footprint 2022-04-03)
Names: Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA
Length: 9
Consensus: TAnnnnTAG
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 76 9 11 0 A
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 11 9 9 67 T
08 86 0 10 0 A
09 9 9 69 9 G
Binding TFs: 3p57_A / 3p57_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 3p57_E
3p57_F
Publications: He J, Ye J, Cai Y, Riquelme C, Liu J.O, Liu X, Han A, Chen L. Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly. Nucleic acids research 39:4464-74 (2011). [Pubmed]

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