DNA Binding Motif

						

			
Accessions: 1je8_EF (3D-footprint 20231221)

			
Names: Nitrate/Nitrite Response Regulator Protein NARL
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Two-Component response regulator NarL/DNA Complex: DNA Bending Found in a High Affinity Site
Length: 16
Consensus: TaCCnAnnnnTnGGtA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02     57     13     13     13      a
03      0     96      0      0      C
04      0     96      0      0      C
05     24     24     24     24      n
06     96      0      0      0      A
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11      0      0      0     96      T
12     24     24     24     24      n
13      0      0     96      0      G
14      0      0     96      0      G
15     13     13     13     57      t
16     96      0      0      0      A
Type: Heterodimer
Binding TFs: 1je8_F (Bacterial regulatory proteins, luxR family, Sigma-70, region 4, Sigma-70, region 4, Winged helix-turn-helix DNA-binding)
1je8_E (Bacterial regulatory proteins, luxR family, Sigma-70, region 4, Sigma-70, region 4, Winged helix-turn-helix DNA-binding)
Binding Sites: 1je8_G / 1je8_H
			
Publications: Maris AE., Sawaya MR., Kaczor-Grzeskowiak M., Jarvis MR., Bearson SM., Kopka ML., Schroder I., Gunsalus RP., Dickerson RE. Dimerization allows DNA target site recognition by the NarL response regulator. Nat Struct Biol. 9(10):771-8 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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