DNA Binding Motif

Accessions: 5yeh_B (3D-footprint 2022-04-03)
Names: Transcriptional repressor CTCF
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of CTCF ZFs4-8-eCBS
Length: 12
Consensus: CgnCCTCTAgnG
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 16 16 64 0 g
03 24 24 24 24 n
04 16 80 0 0 C
05 0 96 0 0 C
06 0 16 0 80 T
07 0 96 0 0 C
08 0 0 0 96 T
09 96 0 0 0 A
10 16 16 56 8 g
11 24 24 24 24 n
12 0 0 96 0 G
Binding TFs: 5yeh_B (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc-finger domain)
Binding Sites: 5yeh_E
5yeh_F
Publications: Yin M, Wang J, Wang M, Li X, Zhang M, Wu Q, Wang Y. Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites. Cell Res 27:1365-1377 (2017). [Pubmed]

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