DNA Binding Motif
| Accessions: | HESX1_DBD_1 (HumanTF 1.0), MA0894.1 (JASPAR 2024) |
| Names: | HESX1 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: monomeric; SELEX cycle: 3, HT-SELEX |
| Length: | 10 |
| Consensus: | gyTAATTrry |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 831 753 1743 744 g 02 879 1432 447 1313 y 03 187 0 34 4072 T 04 4072 0 53 31 A 05 4072 7 9 0 A 06 0 0 15 4072 T 07 0 15 0 4072 T 08 1892 38 2180 97 r 09 1245 772 1681 373 r 10 801 1601 461 1209 y |
| Type: | Heterodimer |
| Binding TFs: | HESX1_DBD (Homeobox domain) Q9UBX0 (Homeobox domain) Q9UBX0 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Brickman JM, Clements M, Tyrell R, McNay D, Woods K, Warner J, Stewart A, Beddington RS, Dattani M. Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders. Development 128:5189-99 (2001). [Pubmed] |
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