DNA Binding Motif

Accessions: RARA_DBD_2 (HumanTF 1.0), MA0729.1 (JASPAR 2024)
Names: RARA
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 18
Consensus: rAGGTCAAAAGGTCAAkk
Weblogo:
PSSM: P0 A C G T
01 250 1 513 4 r
02 507 1 35 0 A
03 0 0 745 0 G
04 1 0 746 19 G
05 0 5 1 559 T
06 2 707 26 0 C
07 528 0 4 0 A
08 526 0 28 162 A
09 526 0 3 37 A
10 522 5 4 0 A
11 0 0 759 1 G
12 0 0 754 101 G
13 3 0 0 546 T
14 0 705 0 2 C
15 540 0 1 0 A
16 539 36 30 181 A
17 2 0 228 328 k
18 0 115 226 212 k
Type: Heterodimer
Binding TFs: P10276 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
RARA_DBD (Zinc finger, C4 type (two domains))
P10276
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Bastien J, Rochette-Egly C. Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene : (2004). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.