DNA Binding Motif

Accessions: 6hb4_ADGJ (3D-footprint 20231221)
Names: Transcription factor A, mitochondrial
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: TFAM in Complex with Site-Y
Length: 84
Consensus: AATTGAnnnnnnnCACAnnnnnAATTGAnnnnnnnCACAGnnnnnATTGAnnnnnnnCACAGnnnnAATTGAnnnnnnnCACAG
Weblogo:
PSSM: P0 A C G T
01 90 1 4 1 A
02 96 0 0 0 A
03 0 0 0 96 T
04 0 0 0 96 T
05 0 0 96 0 G
06 96 0 0 0 A
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 24 24 24 24 n
14 1 90 1 4 C
15 96 0 0 0 A
16 0 96 0 0 C
17 96 0 0 0 A
18 24 24 24 24 n
19 24 24 24 24 n
20 24 24 24 24 n
21 24 24 24 24 n
22 24 24 24 24 n
23 96 0 0 0 A
24 96 0 0 0 A
25 0 0 0 96 T
26 0 0 0 96 T
27 0 0 96 0 G
28 90 1 4 1 A
29 24 24 24 24 n
30 24 24 24 24 n
31 24 24 24 24 n
32 24 24 24 24 n
33 24 24 24 24 n
34 24 24 24 24 n
35 24 24 24 24 n
36 1 93 1 1 C
37 96 0 0 0 A
38 0 96 0 0 C
39 96 0 0 0 A
40 7 8 74 7 G
41 24 24 24 24 n
42 24 24 24 24 n
43 24 24 24 24 n
44 24 24 24 24 n
45 24 24 24 24 n
46 93 1 1 1 A
47 0 0 0 96 T
48 0 0 0 96 T
49 0 0 96 0 G
50 96 0 0 0 A
51 24 24 24 24 n
52 24 24 24 24 n
53 24 24 24 24 n
54 24 24 24 24 n
55 24 24 24 24 n
56 24 24 24 24 n
57 24 24 24 24 n
58 3 82 6 5 C
59 96 0 0 0 A
60 0 96 0 0 C
61 96 0 0 0 A
62 5 5 78 8 G
63 24 24 24 24 n
64 24 24 24 24 n
65 24 24 24 24 n
66 24 24 24 24 n
67 90 4 1 1 A
68 96 0 0 0 A
69 0 0 0 96 T
70 0 0 0 96 T
71 0 0 96 0 G
72 90 4 1 1 A
73 24 24 24 24 n
74 24 24 24 24 n
75 24 24 24 24 n
76 24 24 24 24 n
77 24 24 24 24 n
78 24 24 24 24 n
79 24 24 24 24 n
80 7 74 7 8 C
81 96 0 0 0 A
82 0 96 0 0 C
83 96 0 0 0 A
84 8 3 80 5 G
Type: Heterodimer
Binding TFs: 6hb4_D (HMG (high mobility group) box, Domain of unknown function (DUF1898))
6hb4_G / 6hb4_J (HMG (high mobility group) box, Domain of unknown function (DUF1898))
6hb4_A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Publications: Cuppari A, Fernández-Millán P, Battistini F, Tarrés-Solé A, Lyonnais S, Iruela G, Ruiz-López E, Enciso Y, Rubio-Cosials A, Prohens R, Pons M, Alfonso C, Tóth K, Rivas G, Orozco M, Solà M. DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region. Nucleic Acids Res 47:6519-6537 (2019). [Pubmed]

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