DNA Binding Motif

Accessions: POU2F1_DBD_1 (HumanTF 1.0), MA0785.1 (JASPAR 2024)
Names: POU2F1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 2, HT-SELEX
Length: 12
Consensus: awTATGcwAATt
Weblogo:
PSSM: P0 A C G T
01 5076 1938 1494 2075 a
02 5351 1046 2142 5231 w
03 756 1347 474 10582 T
04 10582 12 29 43 A
05 153 501 213 10582 T
06 186 82 10582 1326 G
07 300 10582 1351 3375 c
08 6932 33 46 3651 w
09 10582 108 879 787 A
10 10582 37 51 158 A
11 1422 457 755 10582 T
12 1976 1840 2504 4262 t
Type: Heterodimer
Binding TFs: POU2F1_DBD (Homeobox domain, Pou domain - N-terminal to homeobox domain)
P14859 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
P14859
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Verrijzer C. P., Alkema M. J., van Weperen W. W., van Leeuwen H. C., Strating M. J. J., van der Vliet P. C. The DNA binding specificity of the bipartite POU domain and its subdomains. EMBO J. 11:4993-5003 (1992). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.