DNA Binding Motif

						

			
Accessions: TFAP2B_DBD_2 (HumanTF 1.0), MA0812.1 (JASPAR 2024)

			
Names: TFAP2B, TFAP2B(var.2)
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 11
Consensus: mGCCysAGGCd
Weblogo: 
PSSM: P0      A      C      G      T
01   1784   1412    232   1121      m
02     36    609   3940     30      G
03      0   4549      4      0      C
04      0   4549      1    158      C
05     16   1204    612   2716      y
06    576   2126   1498    348      s
07   3480    608    446     14      A
08    235      4   4549      2      G
09      6     10   4549      1      G
10     47   4250    299     25      C
11   1822    371   1149   1207      d
Type: Heterodimer
Binding TFs: TFAP2B_DBD (Transcription factor AP-2)
Q92481 (Transcription factor AP-2)
Q92481
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Eckert D, Buhl S, Weber S, Jäger R, Schorle H. The AP-2 family of transcription factors. Genome Biol : (2005;6(13):246.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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