DNA Binding Motif

Accessions: BHLHB2_DBD (HumanTF 1.0), MA0464.2 (JASPAR 2018)
Names: BHLHB2, BHLHE40
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2018 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Cheneby , Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2017) JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Res. doi: 10.1093/nar/gkx1126 [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 2, HT-SELEX
Length: 10
Consensus: vkCACGTGmc
Weblogo:
PSSM: P0 A C G T
01 3824 3025 2926 1447 v
02 1391 481 5000 6222 k
03 59 11222 0 14 C
04 11222 130 78 77 A
05 23 11222 2 32 C
06 66 30 11222 0 G
07 167 248 87 11222 T
08 4 12 11222 72 G
09 5927 5295 129 500 m
10 1544 5706 1385 2587 c
Type: Heterodimer
Binding TFs: O14503 (Helix-loop-helix DNA-binding domain, Hairy Orange)
BHLHB2_DBD (Helix-loop-helix DNA-binding domain)
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Jones S. An overview of the basic helix-loop-helix proteins. Genome Biol : (2004;5(6):226.). [Pubmed]

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