DNA Binding Motif

						

			
Accessions: BHLHB2_DBD (HumanTF 1.0), MA0464.2 (JASPAR 2024)

			
Names: BHLHB2, BHLHE40
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 2, HT-SELEX
Length: 10
Consensus: vkCACGTGmc
Weblogo: 
PSSM: P0      A      C      G      T
01   3824   3025   2926   1447      v
02   1391    481   5000   6222      k
03     59  11222      0     14      C
04  11222    130     78     77      A
05     23  11222      2     32      C
06     66     30  11222      0      G
07    167    248     87  11222      T
08      4     12  11222     72      G
09   5927   5295    129    500      m
10   1544   5706   1385   2587      c
Type: Heterodimer
Binding TFs: O14503 (Helix-loop-helix DNA-binding domain, Hairy Orange)
BHLHB2_DBD (Helix-loop-helix DNA-binding domain)
O14503
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Jones S. An overview of the basic helix-loop-helix proteins. Genome Biol : (2004;5(6):226.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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