DNA Binding Motif

Accessions: 1u8r_GHIJ (3D-footprint 20231221)
Names: Iron-dependent repressor ideR
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions
Length: 17
Consensus: TTAGCACAGGCTGCCCT
Weblogo:
PSSM: P0 A C G T
01 2 2 4 88 T
02 9 9 11 67 T
03 96 0 0 0 A
04 9 7 69 11 G
05 2 88 4 2 C
06 96 0 0 0 A
07 7 67 9 13 C
08 96 0 0 0 A
09 0 0 96 0 G
10 0 0 96 0 G
11 0 96 0 0 C
12 0 0 0 96 T
13 9 9 69 9 G
14 0 96 0 0 C
15 0 96 0 0 C
16 7 69 11 9 C
17 0 0 0 96 T
Type: Heterodimer
Binding TFs: 1u8r_G / 1u8r_I (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain, FeoA domain, Winged helix DNA-binding domain)
1u8r_H / 1u8r_J (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain, FeoA domain, Winged helix DNA-binding domain)
Binding Sites: 1u8r_K
1u8r_L
Publications: Wisedchaisri G, Holmes R.K, Hol W.G. Crystal structure of an IdeR-DNA complex reveals a conformational change in activated IdeR for base-specific interactions. Journal of molecular biology 342:1155-69 (2004). [Pubmed]

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