DNA Binding Motif

Accessions: 5edn_AJ (3D-footprint 20231221)
Names: Homeobox protein Hox-B13
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of HOXB13-DNA(TCG) complex
Length: 22
Consensus: ATAAAnnnCnnTTnnnnTTTAT
Weblogo:
PSSM: P0 A C G T
01 75 4 13 4 A
02 0 0 0 96 T
03 96 0 0 0 A
04 96 0 0 0 A
05 70 4 8 14 A
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 0 96 0 0 C
10 24 24 24 24 n
11 24 24 24 24 n
12 0 0 0 96 T
13 8 8 5 75 T
14 24 24 24 24 n
15 24 24 24 24 n
16 24 24 24 24 n
17 24 24 24 24 n
18 8 8 12 68 T
19 0 0 0 96 T
20 4 4 5 83 T
21 96 0 0 0 A
22 4 5 4 83 T
Type: Heterodimer
Binding TFs: 5edn_A (Homeobox domain)
5edn_J (Homeobox domain)
Binding Sites: 5edn_K
5edn_L
Publications: Morgunova E, Yin Y, Das PK, Jolma A, Zhu F, Popov A, Xu Y, Nilsson L, Taipale J. Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife : (2018). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.