DNA Binding Motif

						

			
Accessions: TFAP2B_DBD_3 (HumanTF 1.0), MA0813.1 (JASPAR 2024)

			
Names: TFAP2B, TFAP2B(var.3)
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 13
Consensus: tGCCCybrGGGCa
Weblogo: 
PSSM: P0      A      C      G      T
01    306    153     95    751      t
02      0    329   1063      0      G
03      0    924      0      0      C
04      0    871      0      0      C
05      5    774     22    136      C
06     32    469    132    571      y
07    147    345    392    384      b
08    583    200    367     41      r
09    292     53    837     11      G
10      0      0   1236      0      G
11      0      0   1346      0      G
12      0    897    163      0      C
13    650    106    179    226      a
Type: Heterodimer
Binding TFs: TFAP2B_DBD (Transcription factor AP-2)
Q92481 (Transcription factor AP-2)
Q92481
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Eckert D, Buhl S, Weber S, Jäger R, Schorle H. The AP-2 family of transcription factors. Genome Biol : (2005;6(13):246.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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