DNA Binding Motif
Accessions: | EGR2_DBD (HumanTF 1.0), MA0472.2 (JASPAR 2024) |
Names: | EGR2 |
Organisms: | Homo sapiens |
Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | Site type: monomeric; SELEX cycle: 3, HT-SELEX |
Length: | 11 |
Consensus: | mCGCCCACGCa |
Weblogo: | |
PSSM: | P0 A C G T 01 1157 679 94 142 m 02 0 1551 28 73 C 03 295 0 3731 222 G 04 6 1558 25 29 C 05 24 1554 15 13 C 06 0 1468 38 277 C 07 2147 110 26 2 A 08 0 1573 2 23 C 09 106 0 4034 171 G 10 4 1585 20 115 C 11 1731 157 542 430 a |
Type: | Heterodimer |
Binding TFs: | EGR2_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger) P11161 (Zinc finger, C2H2 type, Domain of unknown function (DUF3446), Zinc-finger double domain, C2H2-type zinc finger) P11161 |
Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Swirnoff A. H., Milbrandt J. DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol. Cell. Biol. 15:2275-2287 (1995). [Pubmed] |
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