DNA Binding Motif

Accessions: EGR2_DBD (HumanTF 1.0), MA0472.2 (JASPAR 2024)
Names: EGR2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 11
Consensus: mCGCCCACGCa
Weblogo:
PSSM: P0 A C G T
01 1157 679 94 142 m
02 0 1551 28 73 C
03 295 0 3731 222 G
04 6 1558 25 29 C
05 24 1554 15 13 C
06 0 1468 38 277 C
07 2147 110 26 2 A
08 0 1573 2 23 C
09 106 0 4034 171 G
10 4 1585 20 115 C
11 1731 157 542 430 a
Type: Heterodimer
Binding TFs: EGR2_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P11161 (Zinc finger, C2H2 type, Domain of unknown function (DUF3446), Zinc-finger double domain, C2H2-type zinc finger)
P11161
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Swirnoff A. H., Milbrandt J. DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol. Cell. Biol. 15:2275-2287 (1995). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.